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pentobarbital will lower the extent or result of nateglinide by influencing hepatic enzyme CYP2C9/ten metabolism. Use Caution/Observe.pentobarbital decreases levels of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Powerful CYP3A4 inducers can lessen panobinostat concentrations by ~70% and produce remedy fai